selected publications
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academic article
- Deletion of Enigma Homologue from the Z-disc slows tension development kinetics in mouse myocardium. Journal of General Physiology. 151:670-679. 2019
- Recovery of left ventricular function following in vivo reexpression of cardiac myosin binding protein C. Journal of General Physiology. 151:77-89. 2019
- Acting on an impulse (or two): Advantages of high-frequency tetanic onset in skeletal muscle. Journal of General Physiology. 149:297-300. 2017
- Cardiac MyBP-C Regulates the Rate and Force of Contraction in Mammalian Myocardium. Circulation Research. 116:183-192. 2015
- Phosphorylation of Cardiac Myosin-Binding Protein-C Is a Critical Mediator of Diastolic Function. Circulation: Heart Failure. 8:582-594. 2015
- Dissociation of Structural and Functional Phenotypes in Cardiac Myosin-Binding Protein C Conditional Knockout Mice. Circulation. 126:1194-1205. 2012
- Myosin binding protein-C phosphorylation is the principal mediator of protein kinase A effects on thick filament structure in myocardium. Journal of Molecular and Cellular Cardiology. 53:609-616. 2012
- Differential roles of regulatory light chain and myosin binding protein-C phosphorylations in the modulation of cardiac force development: X-ray studies of RLC phosphorylation in skinned murine cardiac muscle. Journal of Physiology. 588:981-993. 2010
- Regulation of contraction in mammalian striated muscles—the plot thick-ens. Journal of General Physiology. 136:21-27. 2010
- Mutation that dramatically alters rat titin isoform expression and cardiomyocyte passive tension. Journal of Molecular and Cellular Cardiology. 44:983-991. 2008
- Overexpression of TEAD-1 in Transgenic Mouse Striated Muscles Produces a Slower Skeletal Muscle Contractile Phenotype. Journal of Biological Chemistry. 283:36154-36167. 2008
- Protein Kinase A–Mediated Phosphorylation of cMyBP-C Increases Proximity of Myosin Heads to Actin in Resting Myocardium. Circulation Research. 103:244-251. 2008
- Radial Displacement of Myosin Cross-bridges in Mouse Myocardium due to Ablation of Myosin Binding Protein-C. Journal of Molecular Biology. 367:36-41. 2007
- Ablation of Myosin-Binding Protein-C Accelerates Force Development in Mouse Myocardium. Biophysical Journal. 90:4119-4127. 2006
- Activation Dependence of Stretch Activation in Mouse Skinned Myocardium: Implications for Ventricular Function. Journal of General Physiology. 127:95-107. 2006
- Cytoplasmic γ-Actin Is Not Required for Skeletal Muscle Development but Its Absence Leads to a Progressive Myopathy. Developmental Cell. 11:387-397. 2006
- Myosin Light Chain 2 Into the Mainstream of Cardiac Development and Contractility. Circulation Research. 99:225-227. 2006
- Basal myosin light chain phosphorylation is a determinant of Ca 2+ sensitivity of force and activation dependence of the kinetics of myocardial force development. American Journal of Physiology: Heart and Circulatory Physiology. 287:H2712-H2718. 2004
- Expression of cardiac troponin T with COOH-terminal truncation accelerates cross-bridge interaction kinetics in mouse myocardium. American Journal of Physiology: Heart and Circulatory Physiology. 287:H1756-H1761. 2004
- Myosin Crossbridge Activation of Cardiac Thin Filaments: Implications for Myocardial Function in Health and Disease. Circulation Research. 94:1290-1300. 2004
- Frank-Starling Relationship: Long on Importance, Short on Mechanism. Circulation Research. 90:13-Nov. 2002
- Cooperative Mechanisms in the Activation Dependence of the Rate of Force Development in Rabbit Skinned Skeletal Muscle Fibers. Journal of General Physiology. 117:133-148. 2001
- Cross-bridge interaction kinetics in rat myocardium are accelerated by strong binding of myosin to the thin filament. Journal of Physiology. 530:263-272. 2001
- PKA accelerates rate of force development in murine skinned myocardium expressing α- or β-tropomyosin. American Journal of Physiology: Heart and Circulatory Physiology. 280:H2732-H2739. 2001
- Aging-dependent depression in the kinetics of force development in rat skinned myocardium. American Journal of Physiology: Heart and Circulatory Physiology. 276:H1511-H1519. 1999
- Role of myosin heavy chain composition in kinetics of force development and relaxation in rat myocardium. Journal of Physiology. 513:171-183. 1998
- Strong Binding of Myosin Modulates Length-Dependent Ca 2+ Activation of Rat Ventricular Myocytes. Circulation Research. 83:602-607. 1998