Physical inactivity, inflammation, and metabolic syndrome risk factors in young women University of Idaho Seed Grant uri icon



  • There is nearly a three-fold increase in prevalence of overweight and obesity as women age from 
    adolescence to young adulthood. Concurrent with this rise in obesity is a rise in cardiovascular 
    disease (CVD) risk. In young women (20-39 years) the prevalence of metabolic syndrome 
    (MetS), defined as a clustering of CVD risk factors, increased by 78% over a 10-year period. The 
    reasons for this rise in prevalence are unknown but may be related to physical inactivity and 
    subclinical inflammation. Thus, the aim of this study is to examine the relative role of sedentary 
    activity, physical activity and inflammation on MetS risk factors in young women. We 
    hypothesize that physical inactivity and inflammation will be significantly related to MetS risk 
    factors and should be considered in the clinical diagnosis of MetS. To meet this aim we will 
    recruit 40 women aged 20-39 years. Participants will undergo a fasting blood draw and 
    measurements of height, weight, blood pressure, body composition and sedentary and physical 
    activity. Results from this study will be submitted for publication and will serve as pilot data to 
    support a grant to study the effects of an exercise intervention on the risk factors of the MetS in 
    young women.