selected publications
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academic article
- Increased duplex stabilization in porphyrin-LNA zipper arrays with structure dependent exciton coupling. Organic and Biomolecular Chemistry. 14:149-157. 2016
- C5-Alkynyl-Functionalized ?-L-LNA: Synthesis, Thermal Denaturation Experiments and Enzymatic Stability. Journal of Organic Chemistry. 79:5062-5073. 2014
- C5-Amino acid functionalized LNA: positively poised for antisense applications. Chemical Communications. 50:9007-9009. 2014
- Synthesis and Biophysical Properties of C5-Functionalized LNA (Locked Nucleic Acid). Journal of Organic Chemistry. 79:5047-5061. 2014
- Synthesis, Hybridization Characteristics, and Fluorescence Properties of Oligonucleotides Modified with Nucleobase-Functionalized Locked Nucleic Acid Adenosine and Cytidine Monomers. Journal of Organic Chemistry. 79:6256-6268. 2014
- Identification and Characterization of Second-Generation Invader Locked Nucleic Acids (LNAs) for Mixed-Sequence Recognition of Double-Stranded DNA. Journal of Organic Chemistry. 78:9560-9570. 2013
- Fluorescent intercalator displacement replacement (FIDR) assay: determination of relative thermodynamic and kinetic parameters in triplex formation--a case study using triplex-forming LNAs.. Nucleic Acids Research. 40. 2012
- Synthesis and hybridization properties of oligonucleotides modified with 5-(1-aryl-1,2,3-triazol-4-yl)-2'-deoxyuridines.. Organic and Biomolecular Chemistry. 10. 2012
- C5-Functionalized DNA, LNA, and ?-L-LNA: Positional Control of Polarity-Sensitive Fluorophores Leads to Improved SNP-Typing.. Chemistry - A European Journal. 17. 2011
- Preparation of C5-functionalized locked nucleic acids (LNAs). Current Protocols in Nucleic Acid Chemistry. Chapter 4. 2011
- Polymerase-directed synthesis of C5-ethynyl locked nucleic acids. Bioorganic and Medicinal Chemistry. 20:6565-6568. 2010
- Pyrene-functionalized triazole-linked 2'-deoxyuridines-probes for discrimination of single nucleotide polymorphisms (SNPs).. Chemical Communications. 46:4929-4931. 2010
- C5-functionalized LNA: unparalleled hybridization properties and enzymatic stability.. Chembiochem: a European Journal of Chemical Biology. 10. 2009
- Optimized DNA-targeting using triplex forming C5-alkynyl functionalized LNA. Chemical Communications. :6756-6758. 2009
- Optimized synthesis of LNA uracil nucleosides. Tetrahedron Letters. 49:7168-7170. 2008