selected publications
-
academic article
- Nicked Invader probes: multistranded and sequence-unrestricted recognition of double-stranded DNA. Organic and Biomolecular Chemistry. 20:1019-1030. 2022
- Serine-gamma PNA, Invader probes, and chimeras thereof: three probe chemistries that enable sequence-unrestricted recognition of double-stranded DNA. Organic and Biomolecular Chemistry. 2022
- Recognition of double-stranded DNA using LNA-modified toehold Invader probes. Organic and Biomolecular Chemistry. 19:9276-9290. 2021
- CTCF binding modulates UV damage formation to promote mutation hot spots in melanoma. Embo Journal. 2021
- Chimeric gammaPNA-Invader probes: Using Intercalator-functionalized Oligonucleotides to Enhance the DNA-targeting Properties of gammaPNA. Organic and Biomolecular Chemistry. 18:1359-1368. 2020
- Impact of non-nucleotidic bulges on recognition of mixed-sequence dsDNA by pyrene-functionalized Invader probes.. Organic and Biomolecular Chemistry. 18:4645-4655. 2020
- Impact of non-nucleotidic bulges on recognition of mixed-sequence dsDNA by pyrene-functionalized Invader probes. Organic and Biomolecular Chemistry. 18:4645-4655. 2020
- Head-to-head comparison of LNA, (MP)gammaPNA, INA and Invader probes targeting mixed-sequence double-stranded DNA. Organic and Biomolecular Chemistry. 18:56-65. 2019
- Recognition of mixed-sequence DNA targets using spermine-modified Invader probes. Organic and Biomolecular Chemistry. 17:8795-8799. 2019
- Synthesis and biophysical characterization of oligonucleotides modified with O2-alkylated RNA monomers featuring substituted pyrene moieties. Organic and Biomolecular Chemistry. 17:609-621. 2019
- Recognition of mixed-sequence DNA using double-stranded probes with interstrand zipper arrangements of O2 '-triphenylene- and coronene-functionalized RNA monomers. Organic and Biomolecular Chemistry. 15:9362-9371. 2017
- 25 years and still going strong: 2'-O-(pyren-1-yl)methylribonucleotides - versatile building blocks for applications in molecular biology, diagnostics and materials science.. Organic and Biomolecular Chemistry. 15:9760-9774. 2017
- Efficient Discrimination of Single Nucleotide Polymorphisms (SNPs) Using Oligonucleotides Modified with C5-Pyrene-Functionalized DNA and Flanking Locked Nucleic Acid (LNA) Monomers. Chemistry - An Asian Journal. 11:1366-1369. 2016
- Merging Two Strategies for Mixed-Sequence Recognition of Double-Stranded DNA: Pseudocomplementary Invader Probes. Journal of Organic Chemistry. 81:3335-3346. 2016
- Next-generation bis-locked nucleic acids with stacking linker and 2 '-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes. Nucleic Acids Research. 44:2007-2019. 2016
- Increased duplex stabilization in porphyrin-LNA zipper arrays with structure dependent exciton coupling. Organic and Biomolecular Chemistry. 14:149-157. 2016
- Mixed-Sequence Recognition of Double-Stranded DNA Using Enzymatically Stable Phosphorothioate Invader Probes. Molecules. 20:13780-13793. 2015
- Recognition of Double-Stranded DNA Using Energetically Activated Duplexes Modified with N2 '-Pyrene-, Perylene-, or CoroneneFunctionalized 2 '-N-Methyl-2 '-amino-DNA Monomers. Journal of Organic Chemistry. 80:5395-5406. 2015
- Bulged Invader probes: activated duplexes for mixed-sequence dsDNA recognition with improved thermodynamic and kinetic profiles. Chemical Communications. 51:15051-15054. 2015
- Invader probes: harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications. Chemical Science. 6:5006-5015. 2015
- Locked nucleic acid (LNA) induced effect on the hybridization and fluorescence properties of oligodeoxyribonucleotides modified with nucleobase-functionalized DNA monomers. Organic and Biomolecular Chemistry. 13:7236-7247. 2015
- Synthesis and characterization of oligodeoxyribonucleotides modified with 2 '-thio-2 '-deoxy-2 '-S-(pyren-1-yl) methyluridine. Bioorganic and Medicinal Chemistry. 25:3999-4004. 2015
- Self-Assembled Monolayers of Thiols Adsorbed on Au/ZnO-Functionalized Silica Nanosprings: Photoelectron Spectroscopy-Analysis and Detection of Vaporized Explosives. ACS Applied Materials and Interfaces. 6:13355-13366. 2014
- C5-Alkynyl-Functionalized ?-L-LNA: Synthesis, Thermal Denaturation Experiments and Enzymatic Stability. Journal of Organic Chemistry. 79:5062-5073. 2014
- C5-Amino acid functionalized LNA: positively poised for antisense applications. Chemical Communications. 50:9007-9009. 2014
- Carbohydrate-Functionalized Locked Nucleic Acids: Oligonucleotides with Extraordinary Binding Affinity, Target Specificity, and Enzymatic Stability. Organic Letters. 16:3308-3311. 2014
- Recognition of double-stranded DNA using energetically activated duplexes with interstrand zippers of 1-, 2- or 4-pyrenyl-functionalized O 2?-alkylated RNA monomers. Organic and Biomolecular Chemistry. 12:7758-7773. 2014
- Synthesis and Biophysical Properties of C5-Functionalized LNA (Locked Nucleic Acid). Journal of Organic Chemistry. 79:5047-5061. 2014
- Synthesis, Hybridization Characteristics, and Fluorescence Properties of Oligonucleotides Modified with Nucleobase-Functionalized Locked Nucleic Acid Adenosine and Cytidine Monomers. Journal of Organic Chemistry. 79:6256-6268. 2014
- C2'-pyrene-functionalized triazole-linked DNA: universal DNA/RNA hybridization probes.. Journal of Organic Chemistry. 77. 2013
- DNA detection on lateral flow test strips: enhanced signal sensitivity using LNA-conjugated gold nanoparticles.. Chemical Communications. 48. 2013
- Fluorescent intercalator displacement replacement (FIDR) assay: determination of relative thermodynamic and kinetic parameters in triplex formation--a case study using triplex-forming LNAs.. Nucleic Acids Research. 40. 2013
- Gold-peptide nanoconjugate cellular uptake is modulated by serum proteins.. Nanomedicine: nanotechnology, biology, and medicine. 8. 2013
- Synthesis and hybridization properties of oligonucleotides modified with 5-(1-aryl-1,2,3-triazol-4-yl)-2'-deoxyuridines.. Organic and Biomolecular Chemistry. 10. 2013
- DNA strands with alternating incorporations of LNA and 2?-O-(pyren-1-yl)methyluridine: SNP-discriminating RNA detection probes. Chemical Science. 4:3447. 2013
- Identification and Characterization of Second-Generation Invader Locked Nucleic Acids (LNAs) for Mixed-Sequence Recognition of Double-Stranded DNA. Journal of Organic Chemistry. 78:9560-9570. 2013
- Invaders: Recognition of Double-Stranded DNA by Using Duplexes Modified with Interstrand Zippers of 2?- O -(Pyren-1-yl)methyl-ribonucleotides. Chembiochem: a European Journal of Chemical Biology. 14:1534-1538. 2013
- Recognition of Mixed-Sequence DNA Duplexes: Design Guidelines for Invaders Based on 2?- O -(Pyren-1-yl)methyl-RNA Monomers. Journal of Organic Chemistry. 78:12040-12048. 2013
- Sandwich assay for mixed-sequence recognition of double-stranded DNA: Invader-based detection of targets specific to foodborne pathogens. Chemical Communications. 49:9851. 2013
- Synthesis and characterization of oligodeoxyribonucleotides modified with 2'-amino-alpha-L-LNA adenine monomers – High-affinity targeting of single-stranded DNA. Journal of Organic Chemistry. 78:12690-12702. 2013
- C5-Functionalized DNA, LNA, and ?-L-LNA: Positional Control of Polarity-Sensitive Fluorophores Leads to Improved SNP-Typing.. Chemistry-A European Journal. 17. 2011
- High-affinity DNA targeting using readily accessible mimics of N2'-functionalized 2'-amino-?-L-LNA.. Journal of Organic Chemistry. 76. 2011
- Preparation of C5-functionalized locked nucleic acids (LNAs). Current Protocols in Nucleic Acid Chemistry. Chapter 4. 2011
- Pyrene-functionalized oligonucleotides and locked nucleic acids (LNAs): tools for fundamental research, diagnostics, and nanotechnology. Chemical Society Reviews. 40:5771-5788. 2011
- Silica Nanosprings Coated with Noble Metal Nanoparticles: Highly Active SERS Substrates. Journal of Physical Chemistry C. 115:453-459. 2011
- Glowing locked nucleic acids: brightly fluorescent probes for detection of nucleic acids in cells. Journal of the American Chemical Society. 132. 2010
- Invader LNA: efficient targeting of short double stranded DNA.. Organic and Biomolecular Chemistry. 8. 2010
- Novel insights into the use of Glowing LNA as nucleic acid detection probes--influence of labeling density and nucleobases.. Bioorganic and Medicinal Chemistry. 20. 2010
- Polymerase-directed synthesis of C5-ethynyl locked nucleic acids. Bioorganic and Medicinal Chemistry. 20:6565-6568. 2010
- Pyrene-functionalized triazole-linked 2'-deoxyuridines-probes for discrimination of single nucleotide polymorphisms (SNPs).. Chemical Communications. 46:4929-4931. 2010
- Hybridization Study of PNA-DNA in the Solution and Surface-Solution Interface for Biosensor Application. Analytical Letters. 42:2485-2495. 2009
- C5-functionalized LNA: unparalleled hybridization properties and enzymatic stability.. Chembiochem: a European Journal of Chemical Biology. 10. 2009
- Functionalized 2 '-Amino-alpha-L-LNA: Directed Positioning of Intercalators for DNA Targeting. Journal of Organic Chemistry. 74:1070-1081. 2009
- Optimized DNA-targeting using triplex forming C5-alkynyl functionalized LNA. Chemical Communications. :6756-6758. 2009
- Parallel RNA-strand recognition by 2 '-amino-beta-L-LNA. Bioorganic and Medicinal Chemistry. 19:2396-2399. 2009
- Selective deacylation of peracylated ribonucleosides. Tetrahedron Letters. 50:1751-1753. 2009
- Chemically modified oligonucleotides with efficient RNase H response. Bioorganic and Medicinal Chemistry. 18:2296-2300. 2008
- Nucleic acid structural engineering using pyrene-functionalized 2'-amino-alpha-L-LNA monomers and abasic sites. Journal of Organic Chemistry. 73:7060-7066. 2008
- Optimized synthesis of LNA uracil nucleosides. Tetrahedron Letters. 49:7168-7170. 2008
- 2 '-N-(Pyren-1-yl)acetyl-2 '-amino-alpha-L-LNA: Synthesis and detection of single nucleoticle mismatches in DNA and RNA targets. Chembiochem: a European Journal of Chemical Biology. 8:1122-1125. 2007
- Dual-probe system using pyrenylmethyl-modified amino-LNA for mismatch detection. Nucleosides Nucleotides and Nucleic Acids. 26:1261-1263. 2007
- N2 '-functionalized 2 '-amino-alpha-L-LNA adenine derivatives - Efficient targeting of single stranded DNA. Nucleosides Nucleotides and Nucleic Acids. 26:1415-1417. 2007
- Pyrene-functionalized 2 '-amino-alpha-L-LNA as potential diagnostic probes. Nucleosides Nucleotides and Nucleic Acids. 26:1407-1409. 2007
- Sensitive SNP dual-probe assays based on pyrene-functionalized 2 '-amino-LNA: Lessons to be learned 2007
- Synthesis and biophysical studies of N2 '-functionalized 2 '-amino-alpha-L-LNA. Nucleosides Nucleotides and Nucleic Acids. 26:1403-1405. 2007
-
chapter
- One-dimensional silica structures and their applications to the biological sciences. Nanomaterials for the Life Sciences: Nanostructured Oxides. Ed. Kumar, Challa S S R. 83-103. 2009
-
conference paper
- Identification of important food pathogens using LNA (Locked Nucleic Acid) probes. Abstracts of Papers of the American Chemical Society. 2010
- BIOL 32-2'-N-(Pyren-1-yl)carbonyl-2'-amino-LNA (locked nucleic acid): A versatile label for nucleic acid detection. Abstracts of Papers of the American Chemical Society. 2008
- CARB 9-N2'-Functionalized 2'-amino-alfa-L-LNA: A novel class of locked nucleic acids as emerging tools for nucleic acid therapeutics and diagnostics. Abstracts of Papers of the American Chemical Society. 2008