Publications in VIVO

Co-author Network

Co-investigator Network

Nathan R Schiele Associate Professor

Positions

Affiliate, Idaho INBRE
Participating Faculty, Institute for Modeling Collaboration and Innovation (IMCI)
Associate Professor, Chemical & Biological Engineering , College of Engineering

Nathan Schiele received his bachelor's degree in mechanical engineering from the University of Dayton in 2007 and his doctorate in biomedical engineering from Rensselaer Polytechnic Institute in 2012. As a graduate student at Rensselaer, his research focused on cell printing and tendon tissue engineering. Prior to joining the University of Idaho, Schiele was an NIH IRACDA postdoctoral fellow at Tufts University in the Department of Biomedical Engineering, where he studied embryonic tendon development. His current research focuses on understanding how mechanical factors influence musculoskeletal tissue function. His research interests include tendon mechanobiology and tendon tissue engineering.

Research Areas

Publications

selected publications

academic article
- Low-cost, open-source cell culture chamber for regulating physiologic oxygen levels. Hardwarex. 11. 2022
- Delivery of bioactive albumin from multi-functional polyampholyte hydrogels. Journal of Applied Polymer Science. 139. 2022
- REGULATORS OF COLLAGEN CROSSLINKING IN DEVELOPING AND ADULT TENDONS. European Cells and Materials. 43:130-152. 2022
- Neonatal Spinal Cord Transection Decreases Hindlimb Weight-Bearing and Affects Formation of Achilles and Tail Tendons. Journal of Biomechanical Engineering. 143:061012. 2021
- Dielectrophoretic Characterization of Tenogenically Differentiating Mesenchymal Stem Cells. Biosensors. 11:50. 2021
- Enhancement and Mechanisms of MC3T3-E1 Osteoblast-like Cell Adhesion to Albumin Through Calcium Exposure. Biotechnology and Applied Biochemistry. 2021
- Akt Signaling is Activated by TGFβ2 and Impacts Tenogenic Induction of Mesenchymal Stem Cells. Stem Cell Research and Therapy. 12:88. 2021
- Dielectrophoresis as a Tool for Electrophysiological Characterization of Stem Cells. Biophysics Review. 1:011304. 2020
- Ex-vivo Quantification of Ovine Pia Arachnoid Complex Biomechanical Properties under Uniaxial Tension. Fluids and Barriers of the CNS. 17:68. 2020
- Tendons from kangaroo rats are exceptionally strong and tough. Scientific Reports. 9:8196. 2019
- TGFbeta2-induced tenogenesis impacts cadherin and connexin cell-cell junction proteins in mesenchymal stem cells. Biochemical and Biophysical Research Communications. 508:889-893. 2019
- Cell-cell junctions in developing and adult tendons.. Tissue barriers. 1695491. 2019
- Onset of neonatal locomotor behavior and the mechanical development of Achilles and tail tendons.. Journal of Biomechanics. 96:109354. 2019
- Developing a Biomimetic Tooth Bud Model. Journal of Tissue Engineering and Regenerative Medicine . 11:3326-3336. 2017
- Embryonically Inspired Scaffolds Regulate Tenogenically Differentiating Cells. Journal of Biomechanics. 49:3281-3288. 2016
- Actin cytoskeleton contributes to the elastic modulus of embryonic tendon during early development. Journal of Orthopaedic Research. 33:874-881. 2015
- Informing tendon tissue engineering with embryonic development. Journal of Biomechanics. 47:1964-1968. 2014
- Adipogenesis of adipose-derived stem cells may be regulated via the cytoskeleton at physiological oxygen levels in vitro. Stem Cell Research and Therapy. 4:79-79. 2013
- Engineering cellular fibers for musculoskeletal soft tissues using directed self-assembly. Tissue engineering. Part A. 19:1223-1232. 2013
- Mechanical factors in embryonic tendon development: potential cues for stem cell tenogenesis. Current Opinion in Biotechnology. 24:843-840. 2013
- Gelatin-based laser direct-write technique for the precise spatial patterning of cells. Tissue Engineering. Part C - Methods. 17:289-298. 2011
- The maintenance of pluripotency following laser direct-write of mouse embryonic stem cells. Biomaterials. 32:1802-1808. 2011
- Laser-based direct-write techniques for cell printing. Biofabrication. 2. 2010
- Laser direct writing of combinatorial libraries of idealized cellular constructs: biomedical applications. Applied Surface Science. 255:5444-5447. 2009

Research

principal investigator on

Background

education and training

Ph.D. in Biomedical Engineering, Rensselaer Polytechnic Institute 2012
M.S. in Biomedical Engineering, Rensselaer Polytechnic Institute 2010
B.S. in Mechanical Engineering, University of Dayton 2007

Contact

full name

Nathan R Schiele