selected publications
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academic article
- Next-generation bis-locked nucleic acids with stacking linker and 2 '-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes. Nucleic Acids Research. 44:2007-2019. 2016
- Identification and Characterization of Second-Generation Invader Locked Nucleic Acids (LNAs) for Mixed-Sequence Recognition of Double-Stranded DNA. Journal of Organic Chemistry. 78:9560-9570. 2013
- Synthesis and characterization of oligodeoxyribonucleotides modified with 2'-amino-alpha-L-LNA adenine monomers – High-affinity targeting of single-stranded DNA. Journal of Organic Chemistry. 78:12690-12702. 2013
- Novel insights into the use of Glowing LNA as nucleic acid detection probes--influence of labeling density and nucleobases.. Bioorganic and Medicinal Chemistry. 20. 2010
- Polymerase-directed synthesis of C5-ethynyl locked nucleic acids. Bioorganic and Medicinal Chemistry. 20:6565-6568. 2010
- Functionalized 2 '-Amino-alpha-L-LNA: Directed Positioning of Intercalators for DNA Targeting. Journal of Organic Chemistry. 74:1070-1081. 2009
- Parallel RNA-strand recognition by 2 '-amino-beta-L-LNA. Bioorganic and Medicinal Chemistry. 19:2396-2399. 2009
- Chemically modified oligonucleotides with efficient RNase H response. Bioorganic and Medicinal Chemistry. 18:2296-2300. 2008
- Nucleic acid structural engineering using pyrene-functionalized 2'-amino-alpha-L-LNA monomers and abasic sites. Journal of Organic Chemistry. 73:7060-7066. 2008
- 2 '-N-(Pyren-1-yl)acetyl-2 '-amino-alpha-L-LNA: Synthesis and detection of single nucleoticle mismatches in DNA and RNA targets. Chembiochem: a European Journal of Chemical Biology. 8:1122-1125. 2007
- Dual-probe system using pyrenylmethyl-modified amino-LNA for mismatch detection. Nucleosides Nucleotides and Nucleic Acids. 26:1261-1263. 2007
- N2 '-functionalized 2 '-amino-alpha-L-LNA adenine derivatives - Efficient targeting of single stranded DNA. Nucleosides Nucleotides and Nucleic Acids. 26:1415-1417. 2007
- Pyrene-functionalized 2 '-amino-alpha-L-LNA as potential diagnostic probes. Nucleosides Nucleotides and Nucleic Acids. 26:1407-1409. 2007
- Sensitive SNP dual-probe assays based on pyrene-functionalized 2 '-amino-LNA: Lessons to be learned 2007
- Synthesis and biophysical studies of N2 '-functionalized 2 '-amino-alpha-L-LNA. Nucleosides Nucleotides and Nucleic Acids. 26:1403-1405. 2007
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conference paper
- BIOL 32-2'-N-(Pyren-1-yl)carbonyl-2'-amino-LNA (locked nucleic acid): A versatile label for nucleic acid detection. Abstracts of Papers of the American Chemical Society. 2008
- CARB 9-N2'-Functionalized 2'-amino-alfa-L-LNA: A novel class of locked nucleic acids as emerging tools for nucleic acid therapeutics and diagnostics. Abstracts of Papers of the American Chemical Society. 2008